Since the 18th CPC National Congress, the CPC Central Committee with Comrade Xi Jinping at its core has responded calmly to the world's great changes unseen in a century, accurately grasped the world's sci-tech development trend, and pushed China's sci-tech innovation onto a new historical stage. Entering the new era, the Party's leadership in sci-tech improvement has formed a multi-pronged practical approach, which takes sci-tech innovation as the core, sci-tech talents as the resource, self-reliance and self-improvement as the support, development strategy as the guidance, institutional innovation as the driving force,and people's interests as the purpose. The new achievements of China's sci-tech innovation in the new era are inseparable from the leadership of the Party and the participation of all parties. The integration between insisting on independent innovation and strengthening international cooperation has been desired for both current interests and long-term interests with both a broad vision and a fine angle. Such kinds of CPC's Leadership experience are valuable spiritual wealth for constructing both a world leader power in science and technology and a socialist modernization leader power.