Humanities and social sciences plays a vital role in talent developing system of universities. In this study, questionnaire surveys and interviews have been applied to conduct a case study on the practice of large category cultivating of humanities and social sciences at University B. Several key issues have been identified, including: overgeneralized setting of large categories which has brought difficulty to align with students' interests; insufficiently reasonable curriculum construction that fails to meet students' real needs; heavy administrative pressures, making it fail to form an organizational identity; prevalence of confusion and anxiety among few students, which is prone to inducing psychological issues. To address them, four practical strategies have been proposed: to establish a comprehensive and orderly Layout of large categories lead by top-level design; to prioritize the discovery of students' interests for their scientific choice of their majors; to implement a flexible and open human-centered management approach with the aim of equality and respect; to promote interdisciplinary integration to construct a distinctive and comprehensive curriculum system.